BPD Related Conditions A Guide to When BPD and Depression Occur Together By Kristalyn Salters-Pedneault, PhD Kristalyn Salters-Pedneault, PhD Kristalyn Salters-Pedneault, PhD, is a clinical psychologist and associate professor of psychology at Eastern Connecticut State University. Learn about our editorial process Updated on August 28, 2020 Medically reviewed Verywell Mind articles are reviewed by board-certified physicians and mental healthcare professionals. Medical Reviewers confirm the content is thorough and accurate, reflecting the latest evidence-based research. Content is reviewed before publication and upon substantial updates. Learn more. by Daniel B. Block, MD Medically reviewed by Daniel B. Block, MD LinkedIn Twitter Daniel B. Block, MD, is an award-winning, board-certified psychiatrist who operates a private practice in Pennsylvania. Learn about our Medical Review Board Print Ghislain & Marie David de Lossy / Getty Images Many people with borderline personality disorder (BPD) also experience problems with depression. In fact, it is very uncommon that BPD and depression do not co-occur. But what is unique about depression in BPD, and how might having both conditions affect your treatment options? What Is Depression? The term depression is actually not a specific diagnosis. Instead, this term refers to the experience of depressed (blue or low) mood. Depression is more than normal sadness. There are a number of mental health conditions that may include elements of depression, including mood disorders, schizoaffective disorder (a psychotic disorder that includes mood symptoms), and some personality disorders (such as BPD). Individuals who experience one or more episodes of depressed mood may be diagnosed with a major depressive disorder or another disorder depending on whether other symptoms are also present. For example, someone who experiences both episodes of depressed mood and elevated mood (mania) may be diagnosed with a bipolar disorder (a condition that is frequently confused with BPD). However, depression may also take other forms, such as is a dysthymic disorder, which is characterized by chronic, low levels of depressed mood. Depression can also happen outside of these diagnostic categories, such as in bereavement. BPD and Depression: Scope of the Problem There is a very high rate of comorbidity between borderline personality disorder (BPD) and depression. This means many people who have BPD also experience problems with depressed mood. One study found that about 96% of patients with BPD met criteria for a mood disorder. In this study, about 83% of patients with BPD also met criteria for the major depressive disorder, and about 39% of patients with BPD also met criteria for dysthymic disorder. Is Depression Different in BPD? Many experts have noticed that depression often presents differently in patients with BPD than in those without. In other words, the quality of depression seems to be different in BPD. For example, whereas depression is typically associated with feelings of sadness or guilt, depression in BPD has been described as being associated with feelings of anger, deep shame (i.e., feeling emotionally like a bad or evil person), loneliness, and emptiness. People with BPD often describe feeling intensely bored, restless, and/or desperately lonely when they are depressed. Further, depressed episodes in people with BPD are often triggered by interpersonal losses (for example, the breakup of a relationship). How Does BPD Affect Depression Treatment? There is fairly conclusive evidence that patients with both a personality disorder and depression have poorer responses to treatment than those without a personality disorder. A meta-analysis of studies examining treatment outcome in individuals with both personality disorders (PDs) and depression found that people with PDs have poorer responses to treatment regardless of the treatment modality (i.e., medications or psychotherapy). The good news is that research has shown that if a patient with both BPD and depression is treated for BPD and sees improvement in those symptoms, the symptoms of depression also seem to lift. This effect seems to only work in one direction (i.e., treatment solely focused on depression does not seem to alleviate BPD symptoms in patients who have both conditions). If you or a loved one are struggling with depression, contact the Substance Abuse and Mental Health Services Administration (SAMHSA) National Helpline at 1-800-662-4357 for information on support and treatment facilities in your area. For more mental health resources, see our National Helpline Database. A Word From Verywell If you think you may suffer from BPD and depression, talk to your mental health provider about the best approach to treatment. Research suggests that treatment focused on the BPD symptoms may be most effective in reducing the symptoms of both conditions. The Best Online Help Resources for Depression 5 Sources Verywell Mind uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. Beatson JA, Rao S. Depression and borderline personality disorder. Med J Aust. 2012;1(4):24-27. doi:10.5694/mjao12.10474 U. S. National Library of Medicine. Depression. U.S. National Library of Medicine. Bipolar disorder. Yoshimatsu K, Palmer B. Depression in patients with borderline personality disorder. Harv Rev Psychiatry. 2014;22(5):266-73. doi:10.1097/HRP.0000000000000045 Newton-Howes G, Tyrer P, Johnson T, et al. Influence of personality on the outcome of treatment in depression: Systematic review and meta-analysis. J Pers Disord. 2014;28(4):577-93. doi:10.1521/pedi_2013_27_070 Additional Reading Luca M, Luca A, Calandra C. Borderline personality disorder and depression: An update. Psychiatr Q. 2011;83(3):281-292. doi:10.1007/s11126-011-9198-7. Silk KR. The quality of depression in borderline personality disorder and the diagnostic process. J Pers Disord. 2010;24(1):25-37. doi:10.1521/pedi.2010.24.1.25 By Kristalyn Salters-Pedneault, PhD Kristalyn Salters-Pedneault, PhD, is a clinical psychologist and associate professor of psychology at Eastern Connecticut State University. See Our Editorial Process Meet Our Review Board Share Feedback Was this page helpful? Thanks for your feedback! What is your feedback? 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