BPD Genetic Causes of Borderline Personality Disorder By Kristalyn Salters-Pedneault, PhD Kristalyn Salters-Pedneault, PhD Kristalyn Salters-Pedneault, PhD, is a clinical psychologist and associate professor of psychology at Eastern Connecticut State University. Learn about our editorial process Updated on March 31, 2020 Medically reviewed Verywell Mind articles are reviewed by board-certified physicians and mental healthcare professionals. Medical Reviewers confirm the content is thorough and accurate, reflecting the latest evidence-based research. Content is reviewed before publication and upon substantial updates. Learn more. by David Susman, PhD Medically reviewed by David Susman, PhD David Susman, PhD is a licensed clinical psychologist with experience providing treatment to individuals with mental illness and substance use concerns. Learn about our Medical Review Board Print Mixmike/Getty Images Are you wondering about the genetic causes of borderline personality disorder? You're not alone. Many people wonder why they or a loved one has borderline personality disorder (BPD). Unfortunately, there are no easy answers, but research is getting closer to understanding the causes of BPD. Genetics or Environmental Causes Studies of BPD in families show that first-degree relatives—meaning siblings, children, or parents—of people treated for BPD are ten times more likely to have been treated for BPD themselves than the relatives of people with schizophrenia or bipolar disorder. However, while this suggests that BPD runs in families, studies of this type do not tell us exactly how much of BPD is due to genetics. That's because first-degree relatives share not just genes, but also environments in most situations. For example, siblings may be raised together by the same parents. This means that these studies may reflect, in part, any environmental causes of BPD as well. Twin Studies Show Genetics Play a Large Role in BPD A more direct, though still imperfect, way to study the influence of genes on BPD is to examine rates of BPD among identical versus fraternal twins. Identical twins have the exact same genetic makeup whereas fraternal twins only have similar genetic makeup, just like two regular siblings. There have been a few twin studies of BPD, which have shown that 42% of variation in BPD is caused by genetics and 58% is caused by other factors, such as the environment. This suggests that BPD is fairly strongly related to genetic causes. Yet, most likely an interaction of genes and environment leads to BPD in most people with the disorder. What the Genetic Factor Means What does this mean for you? If you have BPD, it means that it is not your fault. You probably have a genetic predisposition to develop the disorder. Perhaps you have also experienced a few of the environmental events that seem to be linked to BPD in some cases, such as being abused as a child or losing a loved one. You do not have BPD because you are “weak” or “can’t handle things.” There is a reason why you experience the symptoms you do. If you have a first-degree relative with BPD, it means that you may have an increased chance of developing the disorder yourself. However, this by no means guarantees that you will develop BPD. In fact, chances are likely that you will not. Why Treatment Is Essential If you're concerned that you're showing signs of BPD, it's important to get treatment early. This will reduce any risk factors and help alleviate your symptoms. Speak to your doctor about your symptoms, testing for a proper diagnosis, and treatment options. Borderline Personality Disorder Discussion Guide Get our printable guide to help you ask the right questions at your next doctor's appointment. Download PDF Learn the best ways to manage stress and negativity in your life. Sign Up You're in! Thank you, {{form.email}}, for signing up. There was an error. Please try again. If you are a parent and you have BPD, you may be concerned about whether your kids will have BPD too. While it is a possibility, know that even though genes are important, they are not the sole cause of BPD. There may be ways to ensure the environment you provide for your kids reduces their risk. Part of that is ensuring that you get treatment and that you stick with the treatment plan you and your doctor decide on. Psychotherapy may also be an option to help you learn effective parenting skills. Sources Verywell Mind uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. Ahmad A, Ramoz N, Thomas P, Jardi R, Gorwood P. Genetics of Borderline Personality Disorder: Systematic Review and Proposal of an Integrative Model. Neuroscience and Biobehavioral Reviews. 2014;40:6-19. Distel MA, Trull TJ, Derom CA, Thiery EW, Grimmer MA, Martin NG, et al. Heritability of Borderline Personality Disorder Features is Similar Across Three Countries. Psychological Medicine. 2008;38:1219-1229. Gunderson JG, Zanarini MC, Choi-Kain LW, Mithell KS, Jang KL, Hudson JI. Family Study of Borderline Personality Disorder and Its Sectors of Psychopathology. Arch Gen Psychiatry. 2011;68(7):753-762. doi: 10.1001/argenpsychiatry.2011.65. Zanarini MC, Frankenburg FR, Yong L, Raviola G, Reich DB, Hennen J, et al. Borderline Psychopathology in the First-degree Relatives of Borderline and Axis II Comparison Probands. Journal of Personality Disorders. 2004;18(5):449-447. By Kristalyn Salters-Pedneault, PhD Kristalyn Salters-Pedneault, PhD, is a clinical psychologist and associate professor of psychology at Eastern Connecticut State University. See Our Editorial Process Meet Our Review Board Share Feedback Was this page helpful? Thanks for your feedback! What is your feedback? Other Helpful Report an Error Submit Speak to a Therapist for BPD Advertiser Disclosure × The offers that appear in this table are from partnerships from which Verywell Mind receives compensation.