Depression Treatment How Does Stimulating the Vagus Nerve Improve Mental Health? By Ariane Resnick, CNC Ariane Resnick, CNC Facebook Ariane Resnick, CNC is a mental health writer, certified nutritionist, and wellness author who advocates for accessibility and inclusivity. Learn about our editorial process Updated on December 21, 2022 Medically reviewed Verywell Mind articles are reviewed by board-certified physicians and mental healthcare professionals. Medical Reviewers confirm the content is thorough and accurate, reflecting the latest evidence-based research. Content is reviewed before publication and upon substantial updates. Learn more. by Shaheen Lakhan, MD, PhD, FAAN Medically reviewed by Shaheen Lakhan, MD, PhD, FAAN Shaheen Lakhan, MD, PhD, is an award-winning physician-scientist and clinical development specialist. Learn about our Medical Review Board Print Natalia Gdovskaia / Getty Images Table of Contents View All Table of Contents What Is the Vagus Nerve? How Does Vagus Nerve Stimulation Work? Treating Depression Treating PTSD How to Stimulate Your Vagus Nerve In recent years, the potential benefits of stimulating the vagus nerve have come to light, and many people have begun to look into doing it themselves. Stimulating the vagus nerve has been used with success for physical conditions such as the treatment of epilepsy and Alzheimer's, and it is now also being used to treat mental health issues. You may wonder what the relationship is between your vagus nerve and your mental health and whether all the talk about stimulating the vagus nerve for mental health is scientifically real or just a trend. And you may even be wondering what the vagus nerve even is, as many of us have never heard of it before recently. Ahead, we'll break down everything you need to know about the vagus nerve and mental health. What Exactly Is the Vagus Nerve? The vagus nerve, which is also known as the vagal nerves, the X cranial nerve, and the tenth cranial nerve, is the main nerve of your parasympathetic nervous system. The parasympathetic nervous system handles functions like digestion, heart rate, mood, and speech. The vagus nerve runs all the way from our heads to our intestines, on both sides of the spine, connecting through the brain, neck, chest, and stomach. It can have an anti-inflammatory effect on one's body, which makes it useful for treating a wide array of problems. Vagus Nerve Research Is Not a New Thing Though the vagus nerve's functionality only became popular in the mainstream in recent years, stimulation of it has been practiced for decades, and studies around it actually began back in the 1930s. How Does Vagus Nerve Stimulation Work? Stimulation of the vagus nerve is a surgical procedure. A neurosurgeon performs the surgery in an outpatient context. In addition to an implant, there are ways to stimulate this nerve on your own, without medical intervention; we'll get into those options ahead. Vague Nerve Stimulation for Depression Patients with treatment-resistant depression who experienced vagus nerve stimulation proved to have better rates of remission than those who didn't and were able to retain those results for years. Depression can be resistant to treatment with medication or lifestyle changes, so the device offers an alternative to the more common treatments used. It can be used for both adults and children, with one study noting that "the preliminary data show that it remains a promising treatment option and may provide long-term benefit for children with depression." Vagus Nerve Stimulation for PTSD Post-traumatic stress disorder, also known as PTSD, can impact the lives of trauma victims for a lifetime. PTSD patients who were studied had a positive response to vagus nerve stimulation, and this success has held for those who simultaneously had traumatic brain injuries (TBIs) as well. Because TBIs can cause additional mental health issues, it's particularly promising that the treatment was able to aid in the reduction of symptoms regardless of this complexity. PTSD patients also reduced their anxiety levels thanks to this treatment. How to Stimulate Your Vagus Nerve for Mental Health These are the various ways that the vagus nerve can be stimulated, resulting in benefits such as reduced depression and anxiety. Stimulating the vagus nerve can also result in physical benefits like a lower heart rate and stronger immunity. Surgical Implantation Vagus nerve stimulation via a surgically-implanted device is FDA-approved for the treatment of chronic and recurring depression in patients over 12 years old. Incisions are made in both your neck and your chest, near your armpit, and a pulse generator is implanted in your chest through the chest incision. The device is battery-powered and about the size of a stopwatch. A wire connects it to your vagus nerve through the incision in your neck. The device is turned on at a separate appointment that occurs weeks after the surgery. When Do People Start to See Results? Depending on the condition being treated, the time it takes to see an improvement in your symptoms may vary. For instance, for those with depression, it may take one year to really see a difference. For people with epilepsy, some patients saw improvements in either one, two, or three years. Breathwork Commonly used in conjunction with yoga, breathwork has been shown to stimulate the vagus nerve. It provides stress relief, can boost cognitive functioning, and may assist with improving executive functioning. Breathwork can be as simple as simply slowing down and focusing on your breathing, or you can try more complex versions of it. One simple and popular method is to consciously breathe in while counting upward, such as from one to ten, then breathe out while counting downward, such as from ten to one. If it sounds hard to try on your own, there are apps available that can walk you through how to do breathwork, and it can be effective with just a few minutes of practice. Cold Plunging Cold plunging, which is the act of immersing oneself in a tub of ice-cold water, has become very popular among wellness enthusiasts. They may be on to something—cold exposure has been shown to stimulate the vagus nerve, resulting in lower heart rate variability and stress reduction. One study noted that "the results demonstrate a pattern of cardiovascular reactivity to cold stimulation, suggesting an increase in cardiac-vagal activation. The effect was significant for cold stimulation in the lateral neck area." This means that the vagus nerve was stimulated specifically through exposure to cold at the neck, the area of the body where it begins. By Using Your Voice People often sing or chant because it feels good to do it, and it turns out that it also stimulates your vagus nerve—that could explain the sense of well-being that some people experience when they do those activities. It's the act of using your voice and your throat that seems to do it. Studies conducted where participants chanted "OHM" showed that the vagus nerve was stimulated in response. If chanting isn't for you, singing may have similar benefits. Some people even believe that gargling is sufficient because of the usage of the throat involved. Reflexology Massage Reflexology involves massaging the feet to stimulate various areas of our bodies. Foot reflexology has been shown to stimulate the vagus nerve. It's also useful for lowering blood pressure, which is one function of the vagus nerve, and the effects occur in both healthy people and those with cardiovascular disease. Reflexology is typically considered alternative or complementary medicine, but studies show that it can be useful for many purposes, including this one. Getting Exercise Regular exercise is associated with everything from increased immunity to longer lifespans. Therefore, it shouldn't be surprising that exercise is also shown to stimulate the vagus nerve. The good news is that vagus nerve stimulation through exercise isn't dependent on one specific type. You can run, dance, ski, swim, or do anything else you enjoy that makes you break a sweat. A Word From Verywell If you're experiencing mental health issues, stimulating your vagus nerve may be one way to help you through them. However, it isn't a replacement for therapy or medication. It's best to discuss new modalities with your practitioner, who can help you learn what may work best for you in your unique situation. I Tried It: Vagus Nerve Exercises 14 Sources Verywell Mind uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. Vagus nerve | definition, function, & facts | britannica [Internet]. [cited 2022 Sep 21]. Ogbonnaya S, Kaliaperumal C. Vagal nerve stimulator: Evolving trends. J Nat Sci Biol Med. 2013;4(1):8–13. Aaronson ST, Sears P, Ruvuna F, Bunker M, Conway CR, Dougherty DD, et al. A 5-year observational study of patients with treatment-resistant depression treated with vagus nerve stimulation or treatment as usual: comparison of response, remission, and suicidality. AJP. 2017 Jul 1;174(7):640–8. Johnson RL, Wilson CG. A review of vagus nerve stimulation as a therapeutic intervention. J Inflamm Res. 2018;11:203-213https://doi.org/10.2147/JIR.S163248 Lamb DG, Porges EC, Lewis GF, Williamson JB. Non-invasive vagal nerve stimulation effects on hyperarousal and autonomic state in patients with posttraumatic stress disorder and history of mild traumatic brain injury: preliminary evidence. Front Med (Lausanne). 2017;4:124. Transcutaneous cervical vagal nerve stimulation in patients with posttraumatic stress disorder (Ptsd): a pilot study of effects on ptsd symptoms and interleukin-6 response to stress. Journal of Affective Disorders Reports. 2021 Dec 1;6:100190. Johnson RL, Wilson CG. A review of vagus nerve stimulation as a therapeutic intervention. J Inflamm Res. 2018;11:203-213. Published 2018 May 16. doi:10.2147/JIR.S163248 Giordano F, Zicca C, Barbra C, Guerrini R, Genitori L. Vagus nerve stimulation: Surgical technique of implantation and revision and related morbidity. Epilepsy Surgery Techniques. 2017. Cleveland Clinic. Vagus Nerve Stimulation (VNS). Gerritsen RJS, Band GPH. Breath of life: the respiratory vagal stimulation model of contemplative activity. Front Hum Neurosci. 2018 Oct 9;12:397. ungmann M, Vencatachellum S, Van Ryckeghem D, Vögele C. Effects of cold stimulation on cardiac-vagal activation in healthy participants: randomized controlled trial. JMIR Form Res. 2018 Oct 9;2(2):e10257 Kalyani BG, Venkatasubramanian G, Arasappa R, Rao NP, Kalmady SV, Behere RV, et al. Neurohemodynamic correlates of ‘OM’ chanting: A pilot functional magnetic resonance imaging study. Int J Yoga. 2011;4(1):3–6. Lu WA, Chen GY, Kuo CD. Foot reflexology can increase vagal modulation, decrease sympathetic modulation, and lower blood pressure in healthy subjects and patients with coronary artery disease. Altern Ther Health Med. 2011 Aug;17(4):8–14. Shimojo G, Joseph B, Shah R, Consolim-Colombo FM, Angelis KD, Ulloa L. Exercise activates vagal induction of dopamine and attenuates systemic inflammation. Brain Behav Immun. 2019 Jan;75:181–91. By Ariane Resnick, CNC Ariane Resnick, CNC is a mental health writer, certified nutritionist, and wellness author who advocates for accessibility and inclusivity. See Our Editorial Process Meet Our Review Board Share Feedback Was this page helpful? Thanks for your feedback! What is your feedback? Other Helpful Report an Error Submit Speak to a Therapist for Depression Advertiser Disclosure × The offers that appear in this table are from partnerships from which Verywell Mind receives compensation.