Addiction Drug Use Opioids How Long Does Heroin Stay in Your System? Heroin in Your Blood, Urine, Hair, & Saliva By Buddy T facebook twitter Buddy T is an anonymous writer and founding member of the Online Al-Anon Outreach Committee with decades of experience writing about alcoholism. Learn about our editorial process Buddy T Medically reviewed by Medically reviewed by Steven Gans, MD on March 08, 2020 Steven Gans, MD is board-certified in psychiatry and is an active supervisor, teacher, and mentor at Massachusetts General Hospital. Learn about our Review Board Steven Gans, MD Updated on March 23, 2020 Print krisanapong detraphiphat / Getty Images Table of Contents View All Table of Contents How Long Does It Take to Feel Effects? How Long Does Heroin Last? Factors That Affect Detection Time How to Get Heroin Out of Your System Symptoms of Overdose Getting Help Heroin is an opiate drug made from morphine. It is not legally available by prescription in the United States, although it is available on a limited basis in Canada, Netherlands, and the United Kingdom to treat heroin addiction. Using heroin brings a high risk of overdose and dangerous interactions with other drugs and prescribed medications. Knowing how long it could be active in your system can help you understand the risks and variables. Heroin is classified as a Schedule I drug, meaning that it's a drug with no currently accepted medical use and a high potential for misuse. Because heroin is so fast-acting and has such a short half-life, it can sometimes be difficult to detect in standard drug screenings. The effects of the drug last for about 30 minutes, but the metabolites produced as the drug is broken down are detectable on standard drug screening tests for around one to four days. How Long Does Heroin Stay in Your System? Blood: Up to six hours Urine: Up to three days Saliva: Up to 24 hours Hair: Up to 90 days What to Know About Heroin Use How Long Does It Take to Feel Effects? Heroin sold on the street is manufactured illegally and differs widely in strength, purity, and what other substances it is mixed with. People who take heroin recreationally use it in many different ways, each of which can affect how soon and how long its effects are felt. Heroin can be smoked, injected, or snorted. The effects of heroin are felt swiftly. Depending on the dose, a wave of intense euphoria lasts 45 seconds to a few minutes, with the other effects peaking for one to two hours and most effects wearing off in three to five hours, although sedation can last longer. Common effects are a surge of euphoria followed by a drowsy twilight state alternating between wake and sleep. Physical effects include constricted pupils, feelings of nausea, flushed skin, and dry mouth, and a feeling of having heavy hands and feet. The Feeling of Getting High on Heroin How Long Does Heroin Last? Heroin has an extremely rapid half-life of two to six minutes and is metabolized to 6-acetyl morphine and morphine. The half-life of morphine is one and a half to seven hours and the half-life of 6-acetyl morphine is just six to 25 minutes. It takes four to five half-lives for a drug to be effectively eliminated from the system. Heroin and 6-acetyl morphine enter the brain more readily than morphine. In the brain and nervous system, these substances act on receptors involved with euphoria, pain suppression, depressing breathing, drowsiness, dysphoria, and rarely delusions and hallucinations. Urine Urine tests are the most frequently used type of drug screening because they are less costly and easy to administer. Heroin can be detected on a standard urine test for between one to four days after the last use. Blood Research has also shown that the 6-AM assay test, originally developed as a urine test, is sensitive enough to detect heroin metabolites in blood. Such tests may be useful for following traffic accidents or overdoses to distinguish between recent heroin use and the therapeutic intake of opioids for pain relief. Saliva The National Highway Traffic Safety Administration reported that high levels of the heroin metabolite 6-acetyl morphine can be detected in saliva samples. Such tests may be a better indicator of heroin use than urine screens in some situations. However, such tests must be administered fairly quickly after the last use in order to be effective. Hair Heroin can be detected by hair follicle tests for up to 90 days after use. People who have been using heroin for longer periods of time may have much longer hair detection windows, however. False Positive Testing Eating foods containing poppy seeds such as muffins or bagels can lead to a false-positive result for opiates on a drug test. Poppy seeds contain trace amounts of morphine and codeine. While most of this is removed during processing, the tiny amount of opiate residue left is enough to trigger a false-positive result on many drug tests. Consuming poppy seeds may lead to a positive test result within two hours of consumption and are detectable in urine for as long as 60 hours, depending on the amount ingested. Certain medications, including quinolones, rifampin, and diphenhydramine, can also trigger false-positive results for opiates on enzyme-mediated immunoassays (EIAs). Because these tests have good sensitivity and lower costs, they are often used in employment and medical drug screenings. Such tests are, however, more prone to false positives, requiring confirmation testing. Try to avoid food or medications that are known to trigger positive test results and inform the lab about any medications, both prescription and over-the-counter, that you are currently taking. Factors That Affect Detection Time Like most drugs, the main way heroin is eliminated from the body is via the kidneys in urine, but it can also be excreted via sweat, tears, saliva, and feces. Individual Factors How long heroin will show up on a standard drug test depends on several factors such as weight, body mass, and personal metabolism. Overall health, including liver and kidney function, can also play a role in how quickly heroin is processed and cleared from the body. Dosage and Frequency of Use The main factor in how long heroin is detectable in a drug test is the amount of the drug taken. Heroin will stay in the body only one or two days with light use, but with heavy, chronic use, it can remain detectable in a urine test for almost a week. Drug Purity and Drug Interactions Because heroin is illegal, there is little consistency in the purity of the substance. Some doses may be purer and stronger, which will increase the amount of time the drug takes to be eliminated from the body. Interactions with other substances can also affect how quickly heroin is metabolized. Types of Heroin and Its Ingredients How to Get Heroin Out of Your System Heroin is metabolized quickly and is not detectable by most standard drug tests after about three days. The only way to get heroin out of your system is to stop using the drug and allow your body time to metabolize and eliminate it. Stopping heroin cold turkey can often lead to severe withdrawal effects, however, so talk to your doctor about your treatment options. Staying healthy by getting regular exercise and drinking plenty of fluids may help you metabolize the substance more quickly. Symptoms of Overdose While heroin is in a person's system, they are at risk of interactions with other drugs and substances as well as overdose. Street heroin varies in purity from 26% to 47%, and it is often combined with other substances like ketamine, cocaine, diphenhydramine, alprazolam, and MDMA (ecstasy). Heroin depresses the respiratory system and slows the heart rate, so there are risks of interactions that can lead to coma. Dangerous interactions might happen with barbiturates, benzodiazepines, certain antidepressants, and antihistamines. One of the main reasons to be aware of how long heroin remains in the system is the risk of overdose. If you take more heroin because the effects of the last dose have worn off, but the drug is still in your system, it could cause an accidental overdose. Symptoms of a heroin overdose include: Shallow, slow or difficulty breathing Extremely small pupils (pinpoint pupils) Discolored tongue Low blood pressure Weak pulse Bluish-colored nails and lips Spasms of the stomach and intestines Coma Delirium Disorientation Uncontrolled muscle movements The above symptoms are related to an overdose of heroin alone, but heroin sold on the street is often mixed with other substances or drugs that can cause their own set of symptoms. Street heroin cut with the powerful painkiller fentanyl, for example, has caused a noticeable increase in overdose. Understanding Opioid Overdoses Getting Help Heroin is highly addictive and both physical and psychological dependence on the drug can occur quickly. If you want to quit using heroin, there are things that you can do to get through the withdrawal process and succeed in your recovery. If you or a loved one are struggling with substance use or addiction, contact the Substance Abuse and Mental Health Services Administration (SAMHSA) National Helpline at 1-800-662-4357 for information on support and treatment facilities in your area. For more mental health resources, see our National Helpline Database. Acute heroin withdrawal can feel much like a bad case of the flu. Symptoms can begin six to 12 hours after the last dose and last for up to a week. Common symptoms of heroin withdrawal include: Nausea Vomiting Cold sweats Body aches Diarrhea Runny nose Tremors Insomnia Fatigue Anxiety Drug cravings Agitation Acute withdrawal symptoms can be effectively managed in a detox setting with appropriate medications. After withdrawal, there are a number of different recovery options including outpatient and residential treatment. Medication-assisted treatment options for opiate addiction include methadone, Buprenorphine, Naloxone, and Naltrexone. Psychological treatments such as cognitive-behavioral therapy and contingency management have also been shown to be effective in treating heroin addiction. Treatment Options for Heroin Addiction Was this page helpful? Thanks for your feedback! Learn the best ways to manage stress and negativity in your life. Sign Up You're in! Thank you, {{form.email}}, for signing up. There was an error. Please try again. What are your concerns? Other Inaccurate Hard to Understand Submit Article Sources Verywell Mind uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. Ellis AD, Mcgwin G, Davis GG, Dye DW. Identifying cases of heroin toxicity where 6-acetylmorphine (6-AM) is not detected by toxicological analyses. Forensic Sci Med Pathol. 2016;12(3):243-247. doi:10.1007/s12024-016-9780-2 Teklezgi BG, Pamreddy A, Baijnath S, et al. Post heroin dose tissue distribution of 6-monoacetylmorphine (6-MAM) with MALDI imaging. J Mol Histol. 2017;48(4):285-292. doi:10.1007/s10735-017-9726-3 Verstraete AG. Detection times of drugs of abuse in blood, urine, and oral fluid. Ther Drug Monit. 2004;26(2):200-205. doi:10.1097/00007691-200404000-00020 Borriello R, Carfora A, Cassandro P, Petrella R. Clinical and forensic diagnosis of very recent heroin intake by 6-acetylmorphine immunoassay test and LC-MS/MS analysis in urine and blood. Ann Clin Lab Sci. 2015;45(4):414-418. National Highway Traffic Safety Administration. Appendix I: National roadside survey pilot test, oral fluid and blood analytic procedures. 2007. Gryczynski J, Schwartz RP, Mitchell SG, O'Grady KE, Ondersma SJ. Hair drug testing results and self-reported drug use among primary care patients with moderate-risk illicit drug use. Drug Alcohol Depend. 2014;141:44-50. doi:10.1016/j.drugalcdep.2014.05.001 Lachenmeier DW, Sproll C, Musshoff F. Poppy seed foods and opiate drug testing--where are we today? Ther Drug Monit. 2010;32(1):11-18. doi:10.1097/FTD.0b013e3181c0eee0 Maypole J. Drug testing for...poppy seeds? National Institute on Drug Abuse for Teens. 2013. Keary CJ, Wang Y, Moran JR, Zayas LV, Stern TA. Toxicologic testing for opiates: understanding false-positive and false-negative test results. Prim Care Companion CNS Disord. 2012;14(4):PCC.12f01371. doi:10.4088/PCC.12f01371 U.S. Department of Justice Drug Enforcement Administration. 2018 National Drug Threat Assessment. 2018. Boyer EW. Management of Opioid Analgesic Overdose. N Engl J Med. 2012;367(2):146-155. doi:10.1056/NEJMra1202561 Pan S, Jiang H, Du J, et al. Efficacy of Cognitive Behavioral Therapy on Opiate Use and Retention in Methadone Maintenance Treatment in China: A Randomised Trial. PLoS ONE. 2015;10(6):e0127598. doi:10.1371/journal.pone.0127598 Additional Reading Boriello R, Carfora A, Cassandro P, Petrella R. Clinical and forensic diagnosis of very recent heroin intake by 6-acetylmorphone immunoassay test and LC-MS/MS analysis in urine and blood. Ann Clin Lab Sci. 2015;45(4):414-8. National Institute on Drug Abuse. Heroin. 2019. National Institute on Drug Abuse. Heroin. Research Report Series, Updated June 2018.