Addiction Drug Use Opioids How Long Does Withdrawal From Opioids Last? By Erica Jacques Erica Jacques Erica Jacques, OT, is a board-certified occupational therapist at a level one trauma center. Learn about our editorial process Updated on March 26, 2020 Medically reviewed Verywell Mind articles are reviewed by board-certified physicians and mental healthcare professionals. Medical Reviewers confirm the content is thorough and accurate, reflecting the latest evidence-based research. Content is reviewed before publication and upon substantial updates. Learn more. by Steven Gans, MD Medically reviewed by Steven Gans, MD Steven Gans, MD is board-certified in psychiatry and is an active supervisor, teacher, and mentor at Massachusetts General Hospital. Learn about our Medical Review Board Print smartboy10 / DigitalVision Vectors / Getty Images Table of Contents View All Table of Contents Overview Signs & Symptoms Coping & Relief Warnings Long-Term Treatment If you're taking opioids for chronic pain, you may experience withdrawal symptoms when you stop using the medication. Opiate drugs are extremely habit-forming; tolerance, physical dependence, addiction, and withdrawal symptoms are all possible. As a result, there is a high potential for misuse and addiction, even when use begins with a prescription. Prescription opioids include: Codeine Demerol (meperidine) Dilaudid (hydromorphone) Methadone Morphine Oxycontin (oxycodone) Percocet (acetaminophen/oxycodone) Vicodin (hydrocodone) Fentanyl The illicit drug heroin is also an opioid. Cutting out opioids safely involves gradually reducing the painkiller dosage as opposed to stopping the medication outright. Your best bet is to consult with your physician before you stop taking these medications. What Is Precipitated Withdrawal? Overview Opioid withdrawal is not pleasant, but in most cases, it’s not life-threatening. In fact, many people describe it like having a bad flu, with fever and sweating, nausea and vomiting, muscle aches and pain, and insomnia. These symptoms can occur if you try to quit "cold turkey” (suddenly stop the medication)—even if you're only taking the amount prescribed by your doctor. Tapering off the drugs slowly can help avoid some unpleasant withdrawal symptoms. Unfortunately, opioid tolerance builds quickly and the risk of physical dependence with opioids is high. For some, dependence can develop in a mere two weeks, especially if you're taking a large dose. Signs & Symptoms Withdrawal symptoms can range from mild to very severe, depending on the type of drug, frequency of use, severity of dependence, and your overall health. Symptoms of withdrawal can begin six to 30 hours after last use of the drug and can last anywhere from five to 10 days, depending on the type of opioid. Symptoms can include: Early symptoms (within 24 hours of stopping the drug): Anxiety Muscle aches and pains Restless legs Eyes tearing (lacrimation) Excessive sweating Insomnia Frequent yawning Later symptoms: Abdominal crampingDiarrheaDilated pupilsNausea and vomitingRapid heart rateHigher blood pressure If you notice any of these symptoms, or if your withdrawal symptoms become worse, be sure to inform your healthcare provider immediately. Your provider may use tools like the Clinical Opiate Withdrawal Scale (COWS) to determine the stage of withdrawal and assess your level of physical dependence on the drug. Opioid Withdrawal Timeline Withdrawal symptoms begin (short-acting opioids) 6–12 hours after last dose Withdrawal symptoms begin (long-acting opioids) 30 hours after last dose Withdrawal symptoms peak 72 hours after last dose Withdrawal symptoms dissipate Up to 10 days after last dose Coping & Relief You may be able to go through opioid withdrawal at home under the direction of your doctor if you have a strong support system and the appropriate medications. But many people need the support of an inpatient detoxification program or local hospital. To help your physician determine the best route for cutting out opioids, consider keeping a pain journal and track everything related to your painkillers, including: DosageFrequency of usePositive and negative effects Do your best to have a plan before visiting your physician. If you are taking opioids for pain, consider asking yourself questions like the following: What are your expectations? Do you want to simply switch painkillers, or do you want to try and live painkiller free? When transitioning off of narcotic painkillers, your doctor may prescribe other pain-relieving medications to ease withdrawal symptoms and prevent breakthrough pain. Opiate/opioid addiction may also be treated with other drugs that help shorten and alleviate symptoms of withdrawal, including: Acetaminophen (Tylenol), aspirin, or NSAIDs (Ibuprofen) for mild symptomsLoperamide (Imodium) for diarrheaHydroxyzine (Vistaril, Atarax) for nauseaClonidine for symptoms of withdrawalMethadone for long-term maintenanceAntidepressant for co-occurring depression or anxiety Warnings Although the symptoms may not be life-threatening, there are dangerous withdrawal complications that can occur if left untreated. Withdrawal symptoms may include dehydration, hypernatremia (elevated blood sodium level), and heart failure from persistent vomiting and diarrhea. Aspiration, which can cause choking or lung infection, can also occur if you vomit and then breathe in stomach contents into your lungs. Perhaps the biggest danger of withdrawal is a relapse. The opioid withdrawal and detox process reduces your tolerance to the drug, so if you go back to taking the same amount of opioids you previously took, overdose can easily occur. Treatment for Opioid Addiction Long-Term Treatment For most people, symptoms of withdrawal should markedly improve within a few days or weeks. If your symptoms are lingering or getting worse, it’s important to get medical help. Quitting opioids is not easy and you may need long-term recovery support or addiction treatment following withdrawal to stay off the drugs, including: Maintenance medication Support groups (such as Narcotics Anonymous or SMART Recovery) Outpatient therapy Intensive outpatient treatment Inpatient treatment Resources No one expects you to stop taking opioids on your own; help is encouraged and readily available. Even if you have been using a narcotic painkiller for a brief time, you may still be at risk for developing withdrawal symptoms if you quit on your own. If you're taking opioids for pain, talk to your physician about why you want to make a change with your pain medication, and let them help you do it the right (and safe) way. If you or a loved one are struggling with substance use or addiction, contact the Substance Abuse and Mental Health Services Administration (SAMHSA) National Helpline at 1-800-662-4357 for information on support and treatment facilities in your area. For more mental health resources, see our National Helpline Database. A Word From Verywell Experiencing the symptoms of opioid withdrawal can be unpleasant and require proper aftercare to ensure lasting recovery. People who take opioids over a long period of time are at high risk of physical dependence and should consult a doctor about managing withdrawal symptoms should they decide to stop taking the drug. If you or a loved one experiences negative consequences of opioid dependence, you should also talk to your doctor about treatment for opioid use disorder. 3 Sources Verywell Mind uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. Opioid Withdrawal. National Center for Biotechnology Information, U.S. National Library of Medicine. Nicholls L, Bragaw L, Ruetsch C. Opioid dependence treatment and guidelines. Journal of Managed Care & Speciality Pharmacy. 2010;16(1 Supp B):14-21. doi:10.18553/jmcp.2010.16.S1-B.14. Darke S, Larney S, Farrell M. Yes, people can die from opiate withdrawal. Addiction. 2017;112(2):199-200. doi:10.1111/add.13512 Additional Reading Medline Plus. Opiate and Opioid Withdrawal. National Institute on Drug Abuse. Drug Facts: Prescription Opioids. Nicholls L, Bragaw L, Ruetsch C. Opioid dependence treatment and guidelines. Journal of Managed Care & Speciality Pharmacy. 2010;16(1 Supp B):14-21. doi:10.18553/jmcp.2010.16.S1-B.14. The National Alliance of Advocates for Buprenorphine Treatment. Clinical Opiate Withdrawal Scale (COWS). 2011. Wesson DR, Ling W. The clinical opiate withdrawal scale (COWS). J Psychoactive Drugs. 2003;35(2):253-9. doi:10.1080/02791072.2003.10400007 By Erica Jacques Erica Jacques, OT, is a board-certified occupational therapist at a level one trauma center. See Our Editorial Process Meet Our Review Board Share Feedback Was this page helpful? 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