Depression Symptoms What Are the Symptoms of Too Much Vitamin D? Key Signs of Vitamin D Toxicity By Kendra Cherry Kendra Cherry Facebook Twitter Kendra Cherry, MS, is an author and educational consultant focused on helping students learn about psychology. Learn about our editorial process Updated on October 16, 2022 Medically reviewed Verywell Mind articles are reviewed by board-certified physicians and mental healthcare professionals. Medical Reviewers confirm the content is thorough and accurate, reflecting the latest evidence-based research. Content is reviewed before publication and upon substantial updates. Learn more. by Carly Snyder, MD Medically reviewed by Carly Snyder, MD Facebook LinkedIn Twitter Carly Snyder, MD is a reproductive and perinatal psychiatrist who combines traditional psychiatry with integrative medicine-based treatments. Learn about our Medical Review Board Print Verywell / Laura Porter Table of Contents View All Table of Contents Symptoms of Excess Vitamin D Causes of Vitamin D Toxicity Vitamin D Supplement Safety Depression and Vitamin D Deficiency Taking too much vitamin D can lead to an excess of calcium in the blood, resulting in physical symptoms such as frequent urination, weakness, nausea, and vomiting. Vitamin D toxicity also can lead to kidney or bone problems such as kidney stones. What Is Vitamin D? Vitamin D is a key nutrient that helps your body absorb calcium to help build strong bones. It’s also important for your immune system, nervous system, and muscles. A deficiency in this vitamin has also been linked to mental illnesses such as depression and seasonal affective disorder (SAD). About 40% of Americans may be deficient in vitamin D, with Black and Hispanic adults facing the highest risk of deficiency. Many people can benefit from increasing their vitamin D intake to sufficient levels through sun exposure, diet changes, or—if needed—supplementation as recommended by a physician. While a deficiency of this nutrient is a very common problem, it’s also possible—but rare—to have too much vitamin D. Too much vitamin D, also known as vitamin D toxicity or hypervitaminosis D, can pose some serious health risks. This is why discussing any supplementation with your doctor is important to ensure you aren't ingesting a potentially harmful mega dose. The current daily recommended amount of vitamin D is 600 IU per day for adults under the age of 70, and 800 IU for older adults. Up to 4,000 IU per day is generally considered the safe upper limit, however, doses up to 10,000 IU/day have not been shown to cause toxicity. In fact, many cases of vitamin D toxicity have been a result of dosing errors leading to significantly higher amounts being ingested. Essentially, it's not easy to ingest toxic levels of vitamin D. Symptoms of Too Much Vitamin D What happens if you take too much vitamin D? Some signs that you might be getting an excessive amount of vitamin D include: Appetite loss Constipation Dehydration Disorientation Dizziness Fatigue Frequent urination High blood pressure Irritability Muscle weakness Nausea Thirst Tinnitus Vomiting If you are experiencing these symptoms, talk to your doctor. Be sure to tell them which supplements, medications, and substances you take, including their dosages. If your doctor suspects that your symptoms might be linked to too much vitamin D, they may administer lab tests to check your blood serum levels. Vitamin D toxicity can result in other consequences, including kidney and bone problems. Your doctor may also look for signs of the following problems caused by excess vitamin D. Hypercalcemia Taking too much vitamin D can lead to excessive calcium in the blood, which is known as hypercalcemia. Some signs of hypercalcemia include: Appetite lossConstipationDepressionHeadachesMemory problemsThirstTiredness Hypercalcemia is defined as having blood serum calcium levels that are two standard deviations above the mean. Normal calcium levels are between 8.8mg/dL to 10.8mg/dL. Calcium serum levels between 10.5 to 13.9 mg/dL are classified as mild to moderate, but numbers between 14.0 and 16.0 mg/dL are considered a hypercalcemia crisis. Hypercalcemia caused by too much vitamin D can be treated with steroids, but eliminating the source of the excessive D vitamin is also critical. Kidney Problems Hypercalcemia caused by excess vitamin D can also lead to kidney problems or even kidney damage. Because having too much vitamin D increases the absorption of calcium, it can result in the formation of kidney stones. However, evidence also suggests that more serious, long-term kidney damage can also take place. These calcium deposits in the kidneys can lead to a condition known as nephrocalcinosis, which can lead to permanent kidney damage or even kidney failure. Research has found that when people took more than 3,600,000 international units (IU) of vitamin D3, they were more likely to experience kidney damage. Note that these levels are orders of magnitude beyond what you'd get from a little time in the sun or the average multivitamin. Bone Problems While getting enough vitamin D is essential for bone health, too much can actually have a detrimental effect. Some research has found that having too much vitamin D can interfere with the actions of vitamin K2, which is a nutrient that helps keep calcium in the bones. Research has shown that people who take megadoses of vitamin D are more prone to bone fractures. In another study, participants took either 400 IU, 4,000 IU or 10,000 IU of vitamin D over a three-year period. Bone density tests showed no improvement over a 400 IU dose and actually showed decreased density in the highest dose group. Can Nutrient Deficiency Cause Depression? What Causes Vitamin D Toxicity? Vitamin D toxicity is almost always the result of excess supplementation. Because your body regulates vitamin D production, you are unlikely to develop it as a result of sun exposure (although it has been linked to tanning bed exposure). Foods generally do not contain large amounts of vitamin D, so getting an excessive amount in your diet is unlikely. People may begin taking vitamin D supplements in order to address a deficiency or to help relieve symptoms of things like seasonal affective disorder or depression. The problem is that they may go overboard or think that taking more will produce more beneficial effects. Vitamin D Supplement Safety Your body produces vitamin D when exposed to the sun, but many people may not get enough due to a variety of factors. Because of this, people often turn to vitamin D supplements. Unfortunately, it isn’t uncommon for people to overdo it. A 2017 study published in The Journal of the American Medical Association (JAMA) found that between 1999 and 2014, there was an increase in the number of American adults taking daily vitamin D supplements of 1,000 IU or more. Of these, 18% exceeded 1000 IU each day and 3% took more than 4,000 IU per day, which may place them at a higher risk of experiencing some adverse effects related to excessive vitamin D. In most cases, you can get all of the vitamin D you need naturally without supplementation through sun exposure and diet. A 15-minute walk outside each day with your extremities exposed can boost vitamin D production. (Remember to put on sunscreen after 15 minutes of exposure, however). Eating foods that are naturally high in vitamin D or are fortified with the nutrient can help. Foods you can eat to boost your vitamin D levels include: Egg yolksFortified milk, yogurt, or juiceCheeseFatter fish such as tuna or salmonCod liver oil If you do decide to take a vitamin D supplement to correct a deficiency or because you are unable to get an adequate amount through sunlight and diet, always follow your doctor's guidelines and do not take more than recommended amounts. Depression and Vitamin D Deficiency For most people, low vitamin D levels tend to be more of a problem. Deficiency can have a number of health effects, including poor bone health, but it can also impact brain development and functioning. Low levels of vitamin D have been associated with mental health conditions, including seasonal affective disorder, depression, and schizophrenia. However, that does not mean that boosting vitamin D can always cure depression. One randomized controlled trial found insufficient evidence to support the use of vitamin D supplementation as a treatment for depression. If you are experiencing symptoms of depression, whether or not it's seasonal, talk to your doctor before you try to self-medicate with a supplement like vitamin D. Your doctor can assess your health and determine if vitamin D might help or if some other treatment would be more appropriate. A Word From Verywell Vitamin D is important for physical and mental health, but it is important to use caution if you do decide to take a supplement. If you are thinking about taking vitamin D supplements, talk to your doctor first. Research suggests that the potential risks of high dose vitamin D supplementation include an increased risk of kidney stones and bone fractures. Extremely high doses of supplementation are also linked to prostate cancer, pancreatic cancer, and increased mortality. 9 Sources Verywell Mind uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. Parva NR, Tadepalli S, Singh P, et al. Prevalence of vitamin D deficiency and associated risk factors in the US population (2011-2012). Cureus. 2018;10(6). doi:10.7759/cureus.2741 Taylor PN, Davies JS. A review of the growing risk of vitamin D toxicity from inappropriate practice. Br J Clin Pharmacol. 2018;84(6):1121-1127. doi:10.1111/bcp.13573. Cleveland Clinic. Hypercalcemia. Sadiq NM, Naganathan S, Badireddy M. Hypercalcemia. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing. Kaur P, Mishra SK, Mithal A. Vitamin D toxicity resulting from overzealous correction of vitamin D deficiency. Clin Endocrinol (Oxf). 2015;83(3):327-31. doi: 10.1111/cen.12836 Rooney MR, Harnack L, Michos ED, Ogilvie RP, Sempos CT, Lutsey PL. Trends in use of high-dose vitamin D supplements exceeding 1000 or 4000 international units daily, 1999-2014. JAMA. 2017;317(23):2448. doi:10.1001/jama.2017.4392 Burt LA, Billington EO, Rose MS, Raymond DA, Hanley DA, Boyd SK. Effect of high-dose vitamin D supplementation on volumetric bone density and bone strength: A randomized clinical trial. JAMA. 2019;322(8):736. doi:10.1001/jama.2019.11889 Anglin RE, Samaan Z, Walter SD, McDonald SD. Vitamin D deficiency and depression in adults: Systematic review and meta-analysis. Br J Psychiatry. 2013;202:100-7. doi:10.1192/bjp.bp.111.106666. Li G, Mbuagbaw L, Samaan Z, et al. Efficacy of vitamin D supplementation in depression in adults: A systematic review. J Clin Endocrinol Metab. 2014;99(3):757-767. doi:10.1210/jc.2013-3450 By Kendra Cherry Kendra Cherry, MS, is an author and educational consultant focused on helping students learn about psychology. See Our Editorial Process Meet Our Review Board Share Feedback Was this page helpful? Thanks for your feedback! What is your feedback? 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