Addiction Drug Use The Health Effects of Commonly Used Drugs All drug abuse can affect your health By Buddy T Buddy T Facebook Twitter Buddy T is an anonymous writer and founding member of the Online Al-Anon Outreach Committee with decades of experience writing about alcoholism. Learn about our editorial process Updated on March 21, 2021 Medically reviewed by Steven Gans, MD Medically reviewed by Steven Gans, MD on March 21, 2021 Steven Gans, MD is board-certified in psychiatry and is an active supervisor, teacher, and mentor at Massachusetts General Hospital. Learn about our Medical Review Board Print Jupiterimages/The Image Bank/Getty Images One of the myths floating around about drugs is if a particular substance can be used as a medication, it's not harmful. Contrary to what some believe, the abuse or nonmedical use of any drug can have potentially long-lasting effects on your health. The truth is even the "safest" drugs can have negative effects on your health and well-being if they are used too often or over too long a period of time. Besides alcohol (which has its own set of health effects), the following are the most commonly abused drugs in the United States, in order of popularity, and how they can affect your health. If you or a loved one are struggling with substance use or addiction, contact the Substance Abuse and Mental Health Services Administration (SAMHSA) National Helpline at 1-800-662-4357 for information on support and treatment facilities in your area. For more mental health resources, see our National Helpline Database. Marijuana Marijuana is the most commonly used illicit drug in the United States. When smoked, it begins to affect users almost immediately and can last for one to three hours. Users claim that smoking marijuana is not harmful, but scientific evidence proves otherwise. Prescription Drugs According to the National Survey on Drug Use and Health (NSDUH), after marijuana, the most popular drugs of abuse in the U.S. include pain relievers, tranquilizers, stimulants, and sedatives. This involves the nonmedical use of prescription drugs, over-the-counter drugs, and drugs that may be manufactured illegally, such as methamphetamine and ecstasy. The Effects of Oxycontin The Effects of Methamphetamine The Effects of Ecstasy (MDMA) The Danger of Sedative Overdose Cocaine and Crack Cocaine Approximately 2.1 million people in the U.S. use cocaine, making it the third most abused category of drug. Cocaine can be snorted, injected and even smoked in some forms of the drug. In all cases, cocaine is a strong central nervous system stimulant which affects the brain. The Health Effects of Cocaine Effects of Cocaine Hallucinogens Each month, more than a million people in the U.S. use hallucinogens such as LSD, PCP, Ketamine, and DXM, according to NSDUH. Hallucinogens disrupt a person's ability to think and communicate rationally, or even to recognize reality, sometimes resulting in bizarre or dangerous behavior. The Effects of LSD The Effects of PCP The Effects of Ketamine The Effects of Dextromethorphan (DMX) Heroin Of all the illicit drugs available on the market today, heroin is the least commonly abused, with only an estimated 200,000 current users in the United States. That's probably because it is the most addictive of all the street drugs. Whether injected, snorted or smoked, heroin will begin to affect the body's central nervous system almost immediately after it is used. The Health Effects of Heroin Short-Term Effects of Heroin Long-Term Effects of Heroin Has Your Health Been Affected? If you believe that your health has been affected by your use of illicit drugs or nonmedical use of prescription or over-the-counter drugs, seek medical attention immediately. If you need help trying to stop taking drugs there are many help and support resources available. Was this page helpful? Thanks for your feedback! Learn the best ways to manage stress and negativity in your life. Sign Up You're in! Thank you, {{form.email}}, for signing up. There was an error. Please try again. What are your concerns? Other Inaccurate Hard to Understand Submit 0 Sources Verywell Mind uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. Substance Abuse and Mental Health Services Administration, Office of Applied Studies (2008). "Results from the 2014 National Survey on Drug Use and Health: National Findings" January 2015. Speak to a Therapist for Addiction Advertiser Disclosure × The offers that appear in this table are from partnerships from which Verywell Mind receives compensation.