Using Nicotine Lozenges for Quitting Smoking

Guidelines for Using This Smoking Quit Aid

Side effects of Nicotine Lozenges

 Verywell / Gary Ferster 

The nicotine lozenge is a nicotine replacement therapy (NRT) that comes in the form of a small, candy-like, sugar-free tablet in flavors like cinnamon, fruit, and mint. When a nicotine lozenge is placed in the mouth and allowed to dissolve over the course of 20 to 30 minutes, nicotine is absorbed into the bloodstream, relieving short-term cravings to smoke.

You cannot smoke while using nicotine lozenges, so many people use them as a quit aid, though there are many things you should know and understand about these lozenges before using them to help you quit smoking.

Pros and Cons

Nicotine lozenges offer smokers trying to quit and ex-smokers quick relief from cravings that are part of nicotine withdrawal. However, they are not a fail-safe solution.

Lozenges should only be used on an as-needed basis, but since they are similar to candy—both in taste and form—the potential to abuse this quit aid is significant.

While you don't need a doctor's prescription for nicotine lozenges, they are a serious over-the-counter medication that must be used exactly as directed and you need to carefully wean yourself off of them in the amount of time suggested.

Brands and Strengths

Brand names associated with the nicotine lozenge include Commit, Nicorette, and Nicorette Mini Lozenge. All of these brands are made by GlaxoSmithKline and come in multiple strengths:

  • Commit and Nicorette Lozenges come in two strengths: 2 mg and 4 mg
  • Nicorette mini Lozenges are also available in 2mg and 4mg strengths, but they are smaller in size and dissolve up to three times faster than regular Nicorette lozenges


You can choose the correct lozenge strength by knowing when your first cigarette of the day is or was smoked and following these guidelines:

  • First cigarette within 30 minutes of waking: 4 mg
  • First cigarette more than 30 minutes after waking: 2 mg

Nicotine lozenges should be used in the following dosages:

  • Weeks 1 to 6: One lozenge every 1 to 2 hours
  • Weeks 7 to 9: One lozenge every 2 to 4 hours
  • Weeks 10 to 12: One lozenge every 4 to 8 hours

Do not use more than five lozenges in 6 hours or 20 lozenges in a 24-hour period. You should stop using nicotine lozenges by the end of 12 weeks. If you have trouble stopping, consult your doctor.

Because acidic foods and beverages can inhibit the absorption of the nicotine through the lining of the mouth, lozenge manufacturers recommend waiting 15 minutes after eating before using a nicotine lozenge.

Also, you cannot smoke or use any other NRT while using nicotine lozenges as you run the risk of a nicotine overdose.

Side Effects 

Side effects that are commonly associated with nicotine lozenge therapy include:

  • Heartburn
  • Hiccups
  • Nausea/indigestion
  • Sore throat

If you experience any of the following extreme side effects, stop using the nicotine lozenge and contact your doctor immediately:

  • Irregular heartbeat or heart palpitations
  • Mouth sores or other problems
  • Severe throat irritation
  • Symptoms of nicotine overdose, which may include dizziness, vomiting, confusion, blurred vision, and feeling weak

Special Precautions to Consider

You should consult your doctor before using nicotine lozenges if any of the following conditions apply to you:

  • You are pregnant. Smoking is harmful to the fetus, so you should try to quit before you get pregnant, if possible. If you are not able to, it's important to work closely with your doctor to safely quit smoking during pregnancy.
  • You are using certain medications. If you're using Chantix, Zyban, or medications for depression or asthma, dosages may need to be adjusted once you stop smoking. Smokers metabolize some medications more quickly than non-smokers, so be sure to let your doctor know about all medicines you're taking, including vitamins and supplements.
  • You have allergies. You are allergic to any medicines, foods, or other substances.
  • You have experienced cardiac issues. You have heart disease, high blood pressure, angina, or have had a heart attack.
  • You have other health issues. If you have diabetes, an overactive thyroid, blood vessel conditions like Bruegger's disease, an adrenal gland tumor, or stomach ulcers.
  • You are on a special diet. If you are on a low sodium diet or have phenylketonuria (PKU).

Nicotine is poisonous, and lozenges may contain enough nicotine to harm children or pets. Store them in a safe place and contact Poison Control at 800-222-1222 in case of an overdose.

A Word From Verywell

The nicotine lozenge can help you quit smoking, but keep in mind that it is a quit aid, not a miracle worker. The magic for success with smoking cessation lies within you, not a product. Work on developing your resolve to quit smoking one day at a time and be patient.

Adding some online support to your quit program will improve the chance of long-term success with smoking cessation. The beauty of online help is that it is available to you 24/7 because people visit from all over the world. 

Time, determination, and support will help you kick the habit of smoking. Believe that, believe in yourself, and be willing to do the work it takes to quit. You'll find that you can quit smoking, just as others have.

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Article Sources
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  1. Wadgave U, Nagesh L. Nicotine Replacement Therapy: An Overview. Int J Health Sci (Qassim). 2016;10(3):425-35.

  2. Dautzenberg B, Nides M, Kienzler JL, Callens A. Pharmacokinetics, safety and efficacy from randomized controlled trials of 1 and 2 mg nicotine bitartrate lozenges (Nicotinell). BMC Clin Pharmacol. 2007;7:11. doi:10.1186/1472-6904-7-11

  3. Sukhija M, Srivastava R, Kaushik A. Pharmacokinetic characterization of three novel 4-mg nicotine lozenges . Int J Clin Pharmacol Ther. 2018;56(3):113-119. doi:10.5414/CP203097

  4. Baker TB, Piper ME, Mccarthy DE, et al. Time to first cigarette in the morning as an index of ability to quit smoking: implications for nicotine dependence. Nicotine Tob Res. 2007;9 Suppl 4:S555-70. doi:10.1080/14622200701673480

  5. Pack QR, Jorenby DE, Fiore MC, et al. A comparison of the nicotine lozenge and nicotine gum: an effectiveness randomized controlled trial. WMJ. 2008;107(5):237-43.

  6. Mills EJ, Wu P, Lockhart I, Wilson K, Ebbert JO. Adverse events associated with nicotine replacement therapy (NRT) for smoking cessation. A systematic review and meta-analysis of one hundred and twenty studies involving 177,390 individuals. Tob Induc Dis. 2010;8:8. doi:10.1186/1617-9625-8-8

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